The immunogenetic basis of severe infections caused by bacille Calmette-Guérin vaccine and environmental mycobacteria in humans remains largely unknown.
We describe 18 patients from several generations of 12 unrelated families who were heterozygous for 1 to 5 overlapping IFNGR1 frameshift small deletions and a wild-type IFNGR1 allele.
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Many of the crude products for which data are included in the statistics may be used either as fuel or as basic materials from which to derive other chemicals, depending upon prevailing economic conditions.
Notwithstanding these duplications, the statistics are sufficiently accurate to indicate trends in the industry, and to serve as a basis for general com- parison.
' Production exceeds the total conqjiled from the Tariff Commission's monthly reports because of the omis- sion of certain data from the monthly reports of a large producer, and the inclusion of data for some com- panies idiich did not report monthly.
There were 12 independent mutation events at a single mutation site, defining a small deletion hotspot.
Neighbouring sequence analysis favours a small deletion model of slipped mispairing events during replication.
The other reports listed may be purchased from the Superintendent of Documents, U. ' Includes data for anthracene, crude and semlrefined pyridine, shingle-stain oil, and neutral oils pro- duced by tar distillers, and for crude sodium phenolate produced by coke-oven operators. SYNTHETIC ORGANIC CHEMICALS, 1955 5 Crude Products from Petroleum and Natural Gas for Chemical Conversion The crude products that are derived from petroleum and nat- ural gas are related to the intermediates and finished products made from such crudes in much the same way that crude products derived from the distillation of coal tar are related to their inter- mediates and finished products.
^»IOUS.,,y 3 osss'^^imi RECENT REPORTS OF THE UNITED STATES TARIFF COMMISSION ON SYNTHETIC ORGANIC CHEMICALS Synthetic Organic Chemicals, United States Production and Sales, 1951 (Rept. 175, 2d ser., 1952), 45^ * Synthetic Organic Chemicals, United States Production and Sales, 1952 (Rept. 190, 2d ser., 1953) Synthetic Organic Chemicals, United States Production and Sales, 1953 (Rept. 194, 2d ser., 1954), 55^ Synthetic Organic Chemicals, United States Production and Sales, 1954 (Rept. 196, 2d ser., 1955), 60^ MISCELLANEOUS SERIES United States Import Duties (1952), .25 (subscription price) Thirty-ninth Annual Report of the United States Tariff Commission (1955), 25^^ NOTE.^The report preceded by an asterisk (*) is out of print. * The statistics include data only for creosote sold for, or consumed in, wood preserving.
Considerable duplication exists in the statistics on the production and sales of petroleum crudes, because some of these crude chemicals are converted to other crude products derived from petroleum, and because data on production and sales may be reported at successive stages in the conversion processes (see table SA^).
OF DOCUMENTS 3^ r NITED STATES TARIFF COMMISSION SYNTHETIC ORGANIC CHEMICALS United States Production and Sales,, 1955 [GPO €1. * Includes data for tar used or sold for paint, pipe covering, saturating, and other uses. --Statistics for materials produced in coke and gas-retort ovens are caii;lled by the Division of Bi- tuminous Coal, U. Bureau of Mines, and those for materials produced in tar and petroleum refineries are ccnjiiled by the U. Many of the crude products de- rived from petroleum are identical with those derived from coal tar (e.g., benzene, toluene, and xylene).